The following is a list of the most populous incorporated places in the United States. As defined by the United States Census Bureau, an "incorporated place" includes a variety of designations, including a city, town, village, borough, and municipality. Some census-designated places may also be included in the Census Bureau's listing of incorporated places. Consolidated city-counties represent a distinct type of government that includes the entire population of a county, or county equivalent. Some consolidated city-counties, however, include multiple incorporated places. This list presents only that portion (or "balance") of such consolidated city-counties that are not a part of another incorporated place.

Note that this list refers only to the population of individual municipalities within their defined limits, which does not include other municipalities or unincorporated suburban areas within urban agglomerations. A different ranking is evident when considering U.S. metropolitan area populations.