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Fifth Avenue is a major thoroughfare in the center of the borough of Manhattan in New York City, New York, United States. The section of Fifth Avenue that crosses Midtown Manhattan, especially that between 49th Street and 60th Street, is lined with prestigious shops and is consistently ranked among the most expensive shopping streets in the world. The "most expensive street in the world" moniker changes depending on currency fluctuations and local economic conditions from year to year. For several years starting in the mid-1990s, the shopping district between 49th and 57th Streets was ranked as having the world's most expensive retail spaces on a cost per square foot basis. In 2008, Forbes magazine ranked Fifth Avenue as being the most expensive street in the world. Some of the most coveted real estate on Fifth Avenue are the penthouses perched atop the buildings.

Fifth Avenue originates at Washington Square Park in Greenwich Village and runs northwards through the heart of Midtown, along the eastern side of Central Park, where it forms the boundary of the Upper East Side and through Harlem, where it terminates at the Harlem River at 142nd Street. Traffic crosses the river on the Madison Avenue Bridge. Fifth Avenue serves as the dividing line for house numbering in Manhattan. It separates, for example, East Fifty-ninth Street from West Fifty-ninth Street. From this zero point for street addresses, numbers increase in both directions as one moves away from Fifth Avenue, with 1 West Fifty-ninth Street on the corner at Fifth Avenue, and 300 West Fifty-ninth Street located three blocks to the west of it.

New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and entertainment. The home of the United Nations Headquarters, New York is an important center for international affairs and is widely deemed the cultural capital of the world. The city is also referred to as New York City or the City of New York to distinguish it from the state of New York, of which it is a part.

Located on one of the world's largest natural harbors, New York City consists of five boroughs which were consolidated in 1898: The Bronx, Brooklyn, Manhattan, Queens, and Staten Island. With a 2010 United States Census population of 8,175,133 distributed over a land area of just 305 square miles (790 km²), New York is the most densely populated major city in the United States. As many as 800 languages are spoken in New York, making it the most linguistically diverse city in the world. The New York City Metropolitan Area's population is the United States' largest, estimated at 18.9 million people distributed over 6,720 square miles (17,400 km²), and is also part of the most populous combined statistical area in the United States, containing 22.2 million people as of 2009 Census estimates. New York has the largest internet presence of any location in the world; registering 7.1 billion search results as of December 2011.

The taxicabs of New York City, with their distinctive yellow paint, are a widely recognized icon of the city. Taxicabs are operated by private companies and licensed by the New York City Taxi and Limousine Commission. The Commission is a New York City government agency that is best known for its responsibility for the more than 13,237 taxis operating in the city. It also oversees over 40,000 other for-hire vehicles, including "black cars", commuter vans and ambulettes. "Medallion taxis," the familiar yellow cabs, are the only vehicles in the city permitted to pick up passengers in response to a street hail.

The United States of America (also called the United States, the U.S., the USA, America, and the States) is a federal constitutional republic comprising fifty states and a federal district. The country is situated mostly in central North America, where its forty-eight contiguous states and Washington, D.C., the capital district, lie between the Pacific and Atlantic Oceans, bordered by Canada to the north and Mexico to the south. The state of Alaska is in the northwest of the continent, with Canada to the east and Russia to the west, across the Bering Strait. The state of Hawaii is an archipelago in the mid-Pacific. The country also possesses several territories in the Pacific and Caribbean.

At 3.79 million square miles (9.83 million km²) and with over 312 million people, the United States is the third or fourth largest country by total area, and the third largest by both land area and population. It is one of the world's most ethnically diverse and multicultural nations, the product of large-scale immigration from many countries. The U.S. economy is the world's largest national economy, with an estimated 2011 GDP of $15.1 trillion (22% of nominal global GDP and over 19% of global GDP at purchasing-power parity).