Agen Cathedral (French: Cathédrale Saint-Caprais d'Agen) is a Roman Catholic cathedral, and national monument of France, located in Agen.

The cathedral of Saint-Caprais or Saint Caprasius is the seat of the Bishop of Agen. It was initially a collegiate church of canons and became the cathedral of Agen in 1801, replacing the old cathedral of Saint-Etienne, which was destroyed during the Revolution.

The structure dates back to the 12th century and as with many churches in southern France, is in the form of a Latin cross. The nave dates from the 13th century. The bell tower was constructed in the 19th century.

The cathedral appears in one of the earliest color photographs ever taken by Louis Arthur Ducos du Hauron in 1877.