Air Southwest was a British airline owned by Eastern Airways. It operated regional scheduled passenger services in the South West of England. Its main base was Plymouth City Airport, with hubs at Newquay Cornwall Airport and Bristol Airport. The airline employed 145 people and was headed by Managing Director Peter Davies and Deputy Chief Executive Mike Coombes.

The company held a United Kingdom Civil Aviation Authority Type A Operating Licence, permitting it to carry passengers, cargo and mail on aircraft with 20 or more seats.