The Alcázar de Colón, or Columbus Alcazar, located in Santo Domingo, Dominican Republic, is the oldest Viceregal residence in America, and forms part of the Colonial Zone of Santo Domingo World Heritage Site. The building houses the Museo Alcázar de Diego Colón, whose collection exhibits the Caribbean's most important ensemble of European late medieval and Renaissance works of art, which were acquired in the 1950s. The Tapestry collection (spanning from the 15th to 17th centuries) is particularly important and unique in the Caribbean, and includes pieces produced by the Flemish Van Den Hecke family from cartouches created by Charles Le Brun. The Alcázar is the most visited museum in Santo Domingo.
The palace is an impressive construction of coralline blocks that once housed some fifty rooms and a number of gardens and courtyards, although what remains today is about half the size it once was. It was built under Diego Colón, the son of Christopher Columbus; when he became Viceroy of La Española and the Indies in 1509, he ordered the construction of a family home and governor’s mansion between 1510 and 1512.
Ciudad Colonial (Spanish for "Colonial City") is the historic central neighborhood of Santo Domingo and the oldest permanent European settlement of the New World. It has been declared a World Heritage Site by UNESCO. It is colloquially known as "Zona Colonial" (Colonial Zone). The Ciudad Colonial is located on the west bank of the Ozama River, which bisects the city. It covers less than 5 square kilometers.