Avignon Cathedral (Cathédrale Notre-Dame des Doms d'Avignon) is a Roman Catholic cathedral, and a national monument of France, located in Avignon, above the Palais des Papes. It is the seat of the Archbishop of Avignon.

The cathedral is a Romanesque building, mainly of the 12th century, the most prominent feature of which is the gilded statue of the Virgin Mary which surmounts the western tower. Among the many works of art in the interior, perhaps the most beautiful is the mausoleum of Pope John XXII, a masterpiece of Gothic carving of the 14th century.