In vertebrates, it is composed of blood cells suspended in a liquid called blood plasma. Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains dissipated proteins, glucose, mineral ions, hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and blood cells themselves. Albumin is the main protein in plasma, and it functions to regulate the colloidal osmotic pressure of blood. The blood cells are mainly red blood cells (also called RBCs or erythrocytes) and white blood cells, including leukocytes and platelets. The most abundant cells in vertebrate blood are red blood cells. These contain hemoglobin, an iron-containing protein, which facilitates transportation of oxygen by reversibly binding to this respiratory gas and greatly increasing its solubility in blood. In contrast, carbon dioxide is almost entirely transported extracellularly dissolved in plasma as bicarbonate ion.
Horror fiction, horror literature and also horror fantasy is a genre of literature, which is intended to, or has the capacity to frighten its readers, scare or startle viewers/readers by inducing feelings of horror and terror. It creates an eerie and frightening atmosphere. Horror can be either supernatural or non-supernatural. Often the central menace of a work of Horror fiction can be interpreted as a metaphor for the larger fears of a society. The genre has ancient origins which were reformulated in the eighteenth century as Gothic horror, with publication of the Castle of Otranto (1764) by Horace Walpole.