Campobasso (IPA: [kampoˈbasso] ( listen); Campobassan dialect Cambuàsce, IPA: [kambuˈwaʃʃə]) is a city and comune in southern Italy, the capital of the Molise region and of the province of Campobasso. It is located in the high basin of the Biferno river, surrounded by the Sannio and Matese mountains.

Campobasso is renowned for the craftmanship of blades (including scissors and knives), a fact well documented since the 14th century. It is also famous for the production of pears and scamorza (cheese). The city is the home of the University of Molise and of the Archdiocese of Campobasso-Boiano.