In Dublin, Portobello (Irish: Cuan Aoibhinn - meaning 'beautiful harbour') is an area stretching westwards from South Richmond Street as far as Upper Clanbrassil Street bordered on the north by the South Circular Road and on the south by the Grand Canal.

Portobello came into existence as a small suburb south of the city of Dublin in the 18th century, centred around Richmond St. During the following century it was completely developed, transforming an area of private estates and farmland into solid Victorian red-bricked living quarters for the middle classes (on the larger streets), and terraced housing bordering the canal for the working classes.

As a fast-expanding suburb during the 19th century Portobello attracted many upwardly-mobile families whose members went on to play important roles in politics, the arts and the sciences. Towards the end of the century came an influx of Jews, refugees from pogroms in Eastern Europe, which gave the name "Little Jerusalem" to the area.

It is in the postal district of Dublin 8. It is in the local government electoral area of Dublin South East Inner City and the Dáil Constituency of Dublin South–East.