The Collège de France (French pronunciation: [kɔlɛʒ də fʁɑ̃s]) is a higher education and research establishment (Grand établissement) located in Paris, France, in the 5th arrondissement, or Latin Quarter, across the street from the historical campus of La Sorbonne at the intersection of Rue Saint-Jacques and Rue des Écoles. It mainly supports research; it also provides teaching, but to professors and researchers.

It was established in 1530 by King Francis I of France, as an imitation of the Collegium Trilingue in Louvain, at the urging of Guillaume Budé. Of humanist inspiration, this school was established as an alternative to the Sorbonne to promote such disciplines as Hebrew language, Ancient Greek (the first teacher being the celebrated scholar Janus Lascaris) and Mathematics. Initially called Collège Royal, and later Collège des Trois Langues (Latin: Collegium Trilingue), Collège National, Collège Impérial, it was named Collège de France in 1870.

What makes it unique is that each professor is required to give lectures where attendance is free and open to anyone, although some high-level courses are not open to the general public. The school's goal is to "teach science in the making" and therefore the professors are chosen from among the foremost researchers of the day, with no requirement other than that of being at the top of their fields. They are chosen from a variety of disciplines, in both science and the humanities. Even though the motto of the Collège is "Docet Omnia," Latin for "It teaches everything," its goal can be best summed up by Maurice Merleau-Ponty's phrase: "Not preconceived notions, but the idea of free thought" which is burned in golden letters above the main hall of the Collège building.