The demographics of Guatemala are diverse, constituting primarily of Mestizos, Amerindians and Europeans. About 60% of the population speak Spanish, with nearly all of the rest speaking Amerindian languages.

According to the CIA World Fact Book, Mestizo (mixed Amerindian-Spanish - in local Spanish called Ladino) and European made 59.4% of the population, and K'iche 9.1%, Kaqchikel 8.4%, Mam 7.9%, Q'eqchi 6.3%, other Mayan 8.6%, indigenous non-Mayan 0.2%, other 0.1%. Therefore, 40% of the population is Amerindian. Pure European population is not known because the country combines mestizos with whites.

Most of Guatemala's population is rural, though urbanization is accelerating. The predominant religion is Roman Catholicism, once the main faith of the population, into which many indigenous Guatemalans have incorporated traditional forms of worship. Protestantism and traditional Maya religions are practiced by an estimated 40% and 1% of the population, respectively.^{[citation needed]}

Though the official language is Spanish, it is often the second language among the indigenous population. However, the Peace Accords signed in December 1996 provide for the translation of some official documents and voting materials into several indigenous languages (see summary of main substantive accords).