A glove (Middle English from Old English glof) is a garment covering the whole hand. Gloves have separate sheaths or openings for each finger and the thumb; if there is an opening but no covering sheath for each finger they are called "fingerless gloves". Fingerless gloves with one large opening rather than individual openings for each finger are sometimes called gauntlets. Gloves which cover the entire hand or fist but do not have separate finger openings or sheaths are called mittens. Mittens are warmer than gloves made of the same material because fingers maintain their warmth better when they are in contact with each other. Reduced surface area reduces heat loss.

A hybrid of glove and mitten also exists, which contains open-ended sheaths for the four fingers (as in a fingerless glove, but not the thumb) and also an additional compartment encapsulating the four fingers as a mitten would. This compartment can be lifted off the fingers and folded back to allow the individual fingers ease of movement and access while the hand remains covered. The usual design is for the mitten cavity to be stitched onto the back of the fingerless glove only, allowing it to be flipped over (normally held back by Velcro or a button) to transform the garment from a mitten to a glove. These hybrids are called convertible mittens or glittens, a combination of "glove" and "mittens".

Gloves protect and comfort hands against cold or heat, damage by friction, abrasion or chemicals, and disease; or in turn to provide a guard for what a bare hand should not touch. Latex, nitrile rubber or vinyl disposable gloves are often worn by health care professionals as hygiene and contamination protection measures. Police officers often wear them to work in crime scenes to prevent destroying evidence in the scene. Many criminals wear gloves to avoid leaving fingerprints, which makes the crime investigation more difficult. However, the gloves themselves can leave prints that are just as unique as human fingerprints. After collecting glove prints, law enforcement can then match them to gloves that they have collected as evidence. In many jurisdictions the act of wearing gloves itself while committing a crime can be prosecuted as an inchoate offense.