Lake Assal (Arabic: بحيرة عسل‎ Buḥayrah ʿAsal, literally honey lake) is a crater lake in central-eastern Djibouti. It is located at the western end of Gulf of Tadjoura in the Tadjoura Region, touching Dikhil Region, at the top of the Great Rift Valley, some 120 km (75 mi) west of Djibouti city. Lake Assal is a saline lake which lies 155 m (509 ft) below sea level in the Afar Triangle, making it the lowest point on land in Africa and the third lowest land depression on Earth after the Dead Sea and Sea of Galilee. There is no outflow from the lake and, due to high evaporation, the salinity level of its waters is ten times that of the sea, making it the most saline in the world after Don Juan Pond. Lake Assal is the world's largest salt reserve, which is presently exploited under four concessions awarded in 2002 at the southeast end of the lake; the major share of production (nearly 80%) is held by Société d’Exploitation du Lac and Société d’Exploitation du Salt Investment S.A de Djibouti.

The lake, considered a "national treasure", is a protected zone under the law No. 45/AN/04/5L of the National Environmental Action Plan, 2000. However, the law does not define the boundary limits of the lake. Since the exploitation of the salt from the lake was uncontrolled, the Plan has emphasized the need for managing the exploitation to avoid negative impact on the lake environment. The Government of Djibouti has initiated a proposal with UNESCO to declare the Lake Assal zone and the Ardoukoba volcano as a World Heritage Site.