The Madison Avenue Bridge crosses the Harlem River connecting Madison Avenue in Manhattan with East 138th Street in the Bronx in New York City. The bridge is operated and maintained by the New York City Department of Transportation. It was designed by Alfred P. Boller and built in 1910 to replace and double the capacity of another earlier swing bridge dating from 1884.

For 2008, the NYCDOT reported an average daily traffic volume in both directions of 41,740; having reached a peak AADT of 49,487 in 2002.

The Madison Avenue Bridge carries the Bx33 local bus route operated by MTA New York City Transit, the BxM3 and BxM4 express bus routes operated by the MTA Bus Company, and the BxM4C express bus route operated by Westchester County's Bee Line Bus System. The average weekday ridership of the Bx33 bus route is 3,680. The average weekday ridership on the BxM3 bus route is 889. The average weekday ridership on the BxM4 bus route is 572.