Mendoza (locally: [menˈdosa]) is the capital city of Mendoza Province, in Argentina. It is located in the northern-central part of the province, in a region of foothills and high plains, on the eastern side of the Andes. As of the 2001 census [INDEC], Mendoza's population was 110,993. The metropolitan population was 848,660 in 2001, making Greater Mendoza the fourth largest census metropolitan area in the country.

Ruta Nacional 7, the major road running between Buenos Aires and Santiago, runs through Mendoza. The city is a frequent stopover for climbers on their way to Aconcagua (the highest mountain in the Western and Southern Hemispheres) and for adventure travelers interested in mountaineering, hiking, horseback riding, rafting, and other sports. In the winter, skiers come to the city for its easy access to the Andes.

Two of the main industries of Mendoza area are olive oil production and wine making. The region around Greater Mendoza is the largest wine producing area in Latin America. As such, Mendoza is one of nine cities worldwide in the network of Great Capitals of Wine, and the city is an emerging enotourism (Wine tourism) destination and base for exploring the region's hundreds of wineries located along the Argentina Wine Route.