Reggio di Calabria (Italian pronunciation: [ˈrɛddʒo di kaˈlaːbrja]; Sicilian-Calabrian dialect: Rìggiu, Greek-Calabrian: Righi, Greek: Ῥήγιον, Rhégion, Latin: Rhegium), commonly known as Reggio Calabria  listen (help·info) or Reggio, is the biggest city and the most populated comune of Calabria, southern Italy, is the capital of the Province of Reggio Calabria and is the seat of the Regional Council of Calabria.

Reggio is located on the "toe" of the Italian peninsula and is separated from the island of Sicily by the Strait of Messina. It is situated on the slopes of the Aspromonte, a long, craggy mountain range that runs up through the center of the region. The third economic center of mainland Southern Italy, the city proper has a population of more than 186,000 inhabitants spread over 236 km², while the fast-growing urban area numbers 260,000 inhabitants. More than 370,000 people live in the metropolitan area, recognised in 2009 by Italian Republic as the 10th Città Metropolitana ('Metropolitan City') in Italy.