Sakyō-ku (左京区, Sakyō-ku^?) is one of the eleven wards in the city of Kyoto, in Kyoto Prefecture, Japan. It was created in 1929 when it was split off from Kamigyo-ku.

It is located in the north-east corner of Kyoto city. In the east it borders the city of Ōtsu in Shiga Prefecture. In the south Sanjō Street separates it from Higashiyama-ku and Yamashina-ku. In the north it borders the city of Nantan in Kyoto Prefecture and Takashima in Shiga Prefecture. In central Kyoto, the Kamo River flows on the western border of this ward.

In the southern part there are many residential areas and schools. For example, the main campus of Kyoto University is located here, as is Kyoto Institute of Technology and Kyoto Seika University. Areas like Iwakura have been designated urbanization control areas, where large-scale exploitation and erection of tall buildings is restricted. Many rice fields remain in this area. The northern part of Sakyō-ku is mountainous and has a thriving forest industry.