Samos (Greek: Σάμος) is a Greek island in the eastern Aegean Sea, south of Chios, north of Patmos and the Dodecanese, and off the coast of Asia Minor, from which it is separated by the 1.6 kilometres (0.99 mi)-wide Mycale Strait. It is also a separate regional unit of the North Aegean region, and the only municipality of the regional unit.

In ancient times Samos was a particularly rich and powerful city-state. It is home to Pythagoreion and the Heraion of Samos, a UNESCO World Heritage Site that includes the Eupalinian aqueduct, a marvel of ancient engineering. Samos is the birthplace of the Greek philosopher and mathematician Pythagoras, after whom the Pythagorean theorem is named, the philosopher Epicurus, and the astronomer Aristarchus of Samos, the first known individual to propose that the Earth revolves around the sun. Samian wine was well known in antiquity, and is still produced on the island.