Sano di Pietro (1406–1481) was an early Italian Renaissance painter and miniaturist from Siena.
No works by Sano are known before 1443; he apprenticed under Sassetta and Giovanni di Paolo
Sano di Pietro's paintings are housed in the National Gallery and the Cathedral Museum of Siena, the Pinacoteca Vaticana, the Brooklyn Museum of Art, the Lindenau-Museum of Altenburg and the Diocesan Museum of Pienza.