The Basilica of Saint Sabina at the Aventine (Latin: Basilica Sanctae Sabinae, Italian: Basilica di Santa Sabina all'Aventino) is a titular minor basilica and mother church of the Roman Catholic Dominican order in Rome, Italy. Santa Sabina lies high on the Aventine Hill, beside the Tiber, close to the headquarters of the Knights of Malta.

Santa Sabina is an early basilica (5th century), with a classical rectangular plan and columns. The decorations have been restored to their original modesty, mostly white. Together with the light pouring in from the windows, this makes the Santa Sabina an airy and roomy place. Other basilicas, such as Santa Maria Maggiore, are often heavily and gaudily decorated. Because of its simplicity, the Santa Sabina represents the crossover from a roofed Roman forum to the churches of Christendom. Its Cardinal Priest is Jozef Tomko. It is the stational church for Ash Wednesday.