Shinjuku Ni-chōme (新宿二丁目), referred to colloquially as Ni-chōme or simply Nichō, is Area 2 in the Shinjuku District of the Shinjuku Special Ward of Tōkyō, Japan. With Tōkyō home to over 8.2 million people, and Shinjuku known as the noisiest and most crowded of its 23 special wards, Ni-chōme further distinguishes itself as Tōkyō's hub of gay subculture, housing the world's highest concentration of gay bars.

Within close walking distance from three train stations (Shinjuku San-chōme Station, Shinjuku Gyoenmae Station, and Japan's busiest train station, Shinjuku Station), the Shinjuku Ni-chōme neighborhood provides a specialized blend of bars, restaurants, cafes, saunas, love hotels, gay pride boutiques, cruising boxes (hattenba), host clubs, nightclubs, massage parlors, parks, and gay book and video stores. In fact within the five blocks centering on street Naka-Dōri between the BYGS building at the Shinjuku San-chōme Station and the small Shinjuku park three blocks to the east, an estimated 200-300 gay bars and nightclubs provide entertainment.